hrp0086p1-p101 | Bone & Mineral Metabolism P1 | ESPE2016

Effect of Bisphosphonates on Bone Fragility Due to Chronic Liver Disease in Ten Children

Gonzales Emmanuel , Darce Martha , Usardi Alessia , Linglart Agnes

Background: Children suffering from chronic liver disease (CLD) may develop rickets, impaired bone mineralization and are exposed to an increased risk of osteoporotic fractures. Bisphosphonate (BP) is used in children to increase the bone density and reduce the fracture incidence. Up to date, no study showing the effect of this treatment in children suffering from CLD has been reported.Objective and hypotheses: Evaluate the effect of BPs in children with...